Cellular Rejuvenation, Detoxification, and Longevity Optimization with Dr. Phillip Milgram, MD
At AgeReversalMD in La Jolla, California, IV NAD+ Therapy is offered as a cornerstone of advanced regenerative medicine. Under the direction of Dr. Phillip Milgram, MD—a physician with over 47 years of clinical experience and a background in advanced intervention and preventive medicine—this therapy is designed to restore cellular energy, enhance cognitive function, and support whole-body healing.
Whether you are recovering from chronic illness, seeking to optimize your performance, or pursuing age-reversal strategies, IV NAD+ Therapy offers a scientifically grounded, physician-supervised path to renewal.
What Is NAD+?
Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme found in every living cell. It plays a critical role in fundamental biological processes, including:
- Cellular energy production through mitochondrial function
- DNA repair and genomic stability
- Regulation of circadian rhythms
- Neurotransmitter synthesis and brain function
- Immune modulation and inflammation control
- Activation of sirtuins, the proteins associated with longevity and metabolic regulation
As we age, NAD+ levels decline significantly. This decline is accelerated by stress, poor sleep, alcohol use, chronic illness, and environmental toxins. Low NAD+ levels are associated with fatigue, brain fog, metabolic dysfunction, and increased susceptibility to age-related diseases.
Restoring NAD+ levels through intravenous infusion can help reverse these effects and support optimal cellular function.
What Is IV NAD+ Therapy?
IV NAD+ Therapy involves the direct infusion of pharmaceutical-grade NAD+ into the bloodstream. This method bypasses the digestive system, allowing for rapid and efficient absorption at the cellular level. Oral NAD+ supplements and precursors such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) are limited by bioavailability and metabolic conversion. In contrast, IV delivery ensures that NAD+ reaches tissues and mitochondria in therapeutic concentrations.
At AgeReversalMD, NAD+ is freshly compounded and administered using proprietary protocols developed by leading experts in the field. Each infusion is tailored to the patient’s biology, goals, and tolerance, with dosing and frequency adjusted based on clinical response.
Clinical Applications of IV NAD+ Therapy
Dr. Phillip Milgram offers IV NAD+ Therapy as part of a comprehensive treatment plan for a wide range of conditions and wellness goals.
Detoxification and Addiction Recovery
NAD+ has been shown to support the detoxification process in individuals recovering from substance use disorders. It helps reduce withdrawal symptoms, stabilize mood, and accelerate neurological repair. Patients undergoing detox from alcohol, opioids, benzodiazepines, or stimulants may benefit from NAD+ as a supportive therapy.
Cognitive Enhancement and Brain Fog
NAD+ plays a central role in neurotransmitter synthesis and neuronal repair. Patients experiencing brain fog, memory loss, or cognitive decline—whether from aging, chronic stress, or post-viral syndromes—often report improved clarity, focus, and mood following NAD+ infusions.
Chronic Fatigue and Mitochondrial Dysfunction
NAD+ is essential for mitochondrial energy production. Patients with chronic fatigue syndrome, fibromyalgia, or post-viral fatigue may experience increased stamina and reduced symptoms after a series of NAD+ treatments.
Longevity and Age Reversal
NAD+ activates sirtuins and supports DNA repair, two mechanisms closely linked to aging and lifespan. By restoring NAD+ levels, patients may experience:
- Improved metabolic function
- Enhanced sleep quality
- Reduced inflammation
- Slower biological aging
NAD+ therapy is often combined with other regenerative modalities such as therapeutic plasma exchange, hormone optimization, and peptide therapy for synergistic effects.
Immune Support and Post-Viral Recovery
NAD+ has been shown to modulate immune responses and reduce inflammatory cytokines. Patients recovering from viral infections, including Long COVID, may benefit from NAD+ as part of an immune-reset protocol.
Athletic Performance and Recovery
High-performance individuals use NAD+ to accelerate recovery, reduce oxidative stress, and improve endurance. It supports muscle repair, mental clarity, and metabolic efficiency.
What to Expect During Treatment
Each IV NAD+ session at AgeReversalMD is conducted in a private, medically supervised setting. Infusions typically last between two to four hours, depending on the dose and patient tolerance.
Before your session, you will be advised to stay well-hydrated and eat a light meal. During the infusion, you may experience sensations such as warmth, tightness in the chest, or lightheadedness. These are normal and typically resolve with adjustment of the infusion rate.
After treatment, most patients report feeling energized, clear-headed, and mentally refreshed. Some may experience mild fatigue or detox symptoms, especially during the first few sessions. Rest and hydration are encouraged post-infusion.
Personalized Protocols
Dr. Phillip Milgram develops individualized NAD+ protocols based on your health history, current symptoms, and treatment goals. A typical course may include:
- An initial series of 4 to 10 infusions over two to four weeks
- Maintenance infusions monthly or quarterly
- Combination with other therapies such as IV vitamins, peptides, or plasma exchange
Patients undergoing detox or neurological recovery may require more intensive protocols, while those seeking longevity optimization may benefit from periodic maintenance.
Safety and Side Effects
IV NAD+ Therapy is safe when administered by trained professionals using high-quality, sterile compounds. Side effects are generally mild and may include:
- Temporary flushing or warmth
- Nausea or lightheadedness
- Mild fatigue or headache
- Rare allergic reactions
Dr. Milgram and his team monitor every session closely and adjust infusion rates to ensure comfort and safety.
Why Choose Dr. Phillip Milgram and AgeReversalMD?
Dr. Phillip Milgram brings over four decades of clinical experience to every patient encounter. As a former Clinical Instructor and Assistant Clinical Professor at the UCSD School of Medicine, he combines academic rigor with compassionate, personalized care. His expertise in advanced intervention, detoxification, and preventive medicine makes him uniquely qualified to guide patients through NAD+ therapy and beyond.
At AgeReversalMD, patients receive:
- Freshly compounded, pharmaceutical-grade NAD+
- Proprietary infusion protocols tailored to individual needs
- A serene, private clinical environment in La Jolla, CA
- Integrated care that addresses root causes, not just symptoms
Scientific Support
Numerous studies support the use of NAD+ in cellular repair, mitochondrial function, and immune modulation. In the Circulate Trial, NAD+ was used in conjunction with therapeutic plasma exchange to reduce biological age and improve immune markers. Participants experienced enhanced strength, balance, and vitality—especially those with elevated blood sugar and liver enzymes.
Other research has shown that NAD+ supplementation can:
- Improve insulin sensitivity
- Reduce neuroinflammation
- Enhance DNA repair mechanisms
- Support cardiovascular health
These findings position NAD+ as a foundational therapy in the emerging field of cellular medicine.
Schedule a Consultation
If you are ready to explore the benefits of IV NAD+ Therapy, Dr. Phillip Milgram and the team at AgeReversalMD are here to help. Whether you are navigating chronic illness, recovering from stress or trauma, or simply seeking to feel your best, NAD+ may be the key to unlocking your next level of health.
Price: $1250/day